Total GRK 5 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3589C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • GRK5
    • Human Gene Id:
    • 2869
    • Human Swiss Prot No:
    • P34947
    • Mouse Swiss Prot No:
    • Q8VEB1
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • G protein-coupled receptor kinase 5 (EC 2.7.11.16) (G protein-coupled receptor kinase GRK5)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:ATP + [G-protein-coupled receptor] = ADP + [G-protein-coupled receptor] phosphate.,function:Specifically phosphorylates the activated forms of G protein-coupled receptors.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 RGS domain.,tissue specificity:Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney.,
    • Function:
    • protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, G-protein signaling, coupled to cyclic nucleotide second messenger, G-protein signaling, coupled to cAMP nucleotide second messenger, tachykinin receptor signaling pathway, intracellular signaling cascade, regulation of G-protein coupled receptor protein signaling pathway, phosphorylation, second-messenger-mediated signaling, cAMP-mediated signaling, cyclic-nucleotide-mediated signaling, response to drug,
    • Subcellular Location:
    • Cytoplasm. Nucleus. Cell membrane; Peripheral membrane protein. Predominantly localized at the plasma membrane; targeted to the cell surface through the interaction with phospholipids. Nucleus localization is regulated in a GPCR and Ca(2+)/calmodulin-dependent fashion.
    • Expression:
    • Highest levels in heart, placenta, lung > skeletal muscle > brain, liver, pancreas > kidney.