VAMP4 rabbit pAb

  • Catalog No.：YT8036
  • Applications：WB
  • Reactivity：Human;Mouse;Rat
    • Target：
    • VAMP4
    • Fields：
    • >>SNARE interactions in vesicular transport
    • Gene Name：
    • VAMP4
    • Protein Name：
    • VAMP4
    • Human Gene Id：
    • 8674
    • Human Swiss Prot No：
    • O75379
    • Mouse Swiss Prot No：
    • O70480
    • Immunogen：
    • Synthesized peptide derived from human VAMP4
    • Specificity：
    • This antibody detects endogenous levels of VAMP4 at Human, Mouse,Rat
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000
    • Purification：
    • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Vesicle-associated membrane protein 4 (VAMP-4)
    • Observed Band(KD)：
    • 17kD
    • Background：
    • Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008],
    • Function：
    • function:Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.,similarity:Belongs to the synaptobrevin family.,similarity:Contains 1 v-SNARE coiled-coil homology domain.,subcellular location:Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.,subunit:Identified in a complex containing STX6, STX13, VAMP4 and VTI1A.,
    • Subcellular Location：
    • Golgi apparatus, trans-Golgi network membrane ; Single-pass type IV membrane protein . Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.
    • Expression：
    • B-cell,Bone marrow,Epithelium,Liver,Urinary bladder,

    Attributes

    • Code：
    • YT8036
    • Size
    • 40μL / 100μL / 200μL
    • Price$：
    • 150 / 280 / 450
    • Delivery：
    • 2024-07-26
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