FOXP3 Polyclonal Antibody

    • Catalog No.:YT6169
    • Applications:IHC-p,WB
    • Reactivity:Human, Mouse, Rat
      • Gene Name:
      • FOXP3 IPEX JM2
      • Protein Name:
      • FOXP3
      • Human Swiss Prot No:
      • Q9BZS1
      • Immunogen:
      • Synthesized peptide derived from human FOXP3
      • Specificity:
      • This antibody detects endogenous levels of human FOXP3
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • IHC-p 1:50-200, WB 1:500-2000
      • Purification:
      • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • Forkhead box protein P3 (Scurfin)
      • Observed Band(KD):
      • 47
      • Background:
      • forkhead box P3(FOXP3) Homo sapiens The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
      • Function:
      • disease:Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.,function:Probable transcription factor. Plays a critical role in the control of immune response.,online information:FOXP3 entry,online information:FOXP3 mutation db,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,
      • Subcellular Location:
      • nucleus,cytoplasm,protein complex,
      • Products Images
      • Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4° over night, secondary antibody(cat:RS0002)was diluted at 1:10000, 37° 1hour.