FOXP3 Polyclonal Antibody

  • Catalog No.:YT6169
  • Applications:IHC-p,WB
  • Reactivity:Human, Mouse, Rat
    • Gene Name:
    • FOXP3 IPEX JM2
    • Protein Name:
    • FOXP3
    • Human Swiss Prot No:
    • Q9BZS1
    • Immunogen:
    • Synthesized peptide derived from human FOXP3
    • Specificity:
    • This antibody detects endogenous levels of human FOXP3
    • Formulation:
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source:
    • Rabbit
    • Dilution:
    • IHC-p 1:50-200, WB 1:500-2000
    • Purification:
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration:
    • 1 mg/ml
    • Storage Stability:
    • -20°C/1 year
    • Other Name:
    • Forkhead box protein P3 (Scurfin)
    • Observed Band(KD):
    • 47
    • Background:
    • forkhead box P3(FOXP3) Homo sapiens The protein encoded by this gene is a member of the forkhead/winged-helix family of transcriptional regulators. Defects in this gene are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX), also known as X-linked autoimmunity-immunodeficiency syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],
    • Function:
    • disease:Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy.,function:Probable transcription factor. Plays a critical role in the control of immune response.,online information:FOXP3 entry,online information:FOXP3 mutation db,similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 1 fork-head DNA-binding domain.,
    • Subcellular Location:
    • nucleus,cytoplasm,protein complex,