Ox40 Polyclonal Antibody

    • Catalog No.:YT3479
    • Applications:IF,ELISA
    • Reactivity:Human,Mouse,Rat
      • Gene Name:
      • TNFRSF4
      • Protein Name:
      • Tumor necrosis factor receptor superfamily member 4
      • Human Gene Id:
      • 7293
      • Human Swiss Prot No:
      • P43489
      • Mouse Swiss Prot No:
      • P47741
      • Immunogen:
      • The antiserum was produced against synthesized peptide derived from human TNR4. AA range:228-277
      • Specificity:
      • Ox40 Polyclonal Antibody detects endogenous levels of Ox40 protein.
      • Formulation:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • Source:
      • Rabbit
      • Dilution:
      • Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
      • Purification:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • Concentration:
      • 1 mg/ml
      • Storage Stability:
      • -20°C/1 year
      • Other Name:
      • TNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD antigen CD134
      • MolecularWeight(Da):
      • 29341
      • Background:
      • TNF receptor superfamily member 4(TNFRSF4) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008],
      • Function:
      • function:Receptor for TNFSF4/OX40L/GP34.,similarity:Contains 4 TNFR-Cys repeats.,subunit:Interacts with TRAF2, TRAF3 and TRAF5.,
      • Subcellular Location:
      • plasma membrane,integral component of plasma membrane,cell surface,
      • Expression:
      • Brain,
      • Products Images
      • Immunofluorescence analysis of HeLa cells, using TNR4 Antibody. The picture on the right is blocked with the synthesized peptide.