CUTL1 (Phospho Ser1237) rabbit pAb

  • Catalog No.：YP1783
  • Applications：WB
  • Reactivity：Human;Mouse;Rat
    • Target：
    • CUTL1
    • Gene Name：
    • CUX1 CUTL1
    • Protein Name：
    • CUTL1 (Phospho-Ser1237)
    • Human Gene Id：
    • 1523
    • Human Swiss Prot No：
    • P39880
    • Mouse Swiss Prot No：
    • P53564
    • Immunogen：
    • Synthesized peptide derived from human CUTL1 (Phospho-Ser1237)
    • Specificity：
    • This antibody detects endogenous levels of CUTL1 (Phospho-Ser1237) at Human, Mouse,Rat
    • Formulation：
    • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
    • Source：
    • Polyclonal, Rabbit,IgG
    • Dilution：
    • WB 1:500-2000
    • Purification：
    • The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1 mg/ml
    • Storage Stability：
    • -15°C to -25°C/1 year(Do not lower than -25°C)
    • Other Name：
    • Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein cux-1)
    • Molecular Weight(Da)：
    • 166kD
    • Background：
    • The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011],
    • Function：
    • alternative products:Additional isoforms seem to exist,function:May be involved in intra-Golgi retrograde transport.,function:Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer.,miscellaneous:Asn-1290 may participate in regulating DNA-binding activity by promoting homo- and heterodimerization.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CASP family.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-bin
    • Subcellular Location：
    • Nucleus .
    • Expression：
    • Colon,Duodenum,Liver,Umbilical vein,

    Attributes

    • Code：
    • YP1783
    • Size
    • 50μL / 100μL / 200μL
    • Price$：
    • 190 / 340 / 600
    • Delivery：
    • 2024-12-09
    Order

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