• Target：
• VAMP4

• Fields：
• >>SNARE interactions in vesicular transport

• Gene Name：
• VAMP4

• Protein Name：
• VAMP4 (Phospho-Ser30)

• Human Gene Id：
• 8674

• Human Swiss Prot No：
• O75379

• Mouse Swiss Prot No：
• O70480

• Immunogen：
• Synthesized peptide derived from human VAMP4 (Phospho-Ser30)

• Specificity：
• This antibody detects endogenous levels of VAMP4 (Phospho-Ser30) at Human, Mouse,Rat

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000

• Purification：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Vesicle-associated membrane protein 4 (VAMP-4)

• Observed Band(KD)：
• 17kD

• Background：
• Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport. [provided by RefSeq, Jul 2008],

• Function：
• function:Involved in the pathway that functions to remove an inhibitor (probably synaptotagmin-4) of calcium-triggered exocytosis during the maturation of secretory granules. May be a marker for this sorting pathway that is critical for remodeling the secretory response of granule.,similarity:Belongs to the synaptobrevin family.,similarity:Contains 1 v-SNARE coiled-coil homology domain.,subcellular location:Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.,subunit:Identified in a complex containing STX6, STX13, VAMP4 and VTI1A.,

• Subcellular Location：
• Golgi apparatus, trans-Golgi network membrane ; Single-pass type IV membrane protein . Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles.

• Expression：
• B-cell,Bone marrow,Epithelium,Liver,Urinary bladder,

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