CUTL1 (Phospho Ser1215) rabbit pAb
- Catalog No.:YP1769
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- CUTL1
- Gene Name:
- CUX1 CUTL1
- Protein Name:
- CUTL1 (Phospho-Ser1215)
- Human Gene Id:
- 1523
- Human Swiss Prot No:
- P39880
- Mouse Gene Id:
- 13047
- Mouse Swiss Prot No:
- P53564
- Rat Swiss Prot No:
- P53565
- Immunogen:
- Synthesized peptide derived from human CUTL1 (Phospho-Ser1215)
- Specificity:
- This antibody detects endogenous levels of CUTL1 (Phospho-Ser1215) at Human, Mouse,Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP) (Homeobox protein cux-1)
- Molecular Weight(Da):
- 166kD
- Background:
- The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011],
- Function:
- alternative products:Additional isoforms seem to exist,function:May be involved in intra-Golgi retrograde transport.,function:Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer.,miscellaneous:Asn-1290 may participate in regulating DNA-binding activity by promoting homo- and heterodimerization.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CASP family.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-bin
- Subcellular Location:
- Nucleus .
- Expression:
- Colon,Duodenum,Liver,Umbilical vein,
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