USP28 (Phospho Ser67) rabbit pAb
- Catalog No.:YP1754
- Applications:WB
- Reactivity:Human;Mouse;Rat
- Target:
- USP28
- Gene Name:
- USP28 KIAA1515
- Protein Name:
- USP28 (Phospho-Ser67)
- Human Gene Id:
- 57646
- Human Swiss Prot No:
- Q96RU2
- Mouse Gene Id:
- 235323
- Mouse Swiss Prot No:
- Q5I043
- Rat Gene Id:
- 315639
- Rat Swiss Prot No:
- D3ZJ96
- Immunogen:
- Synthesized peptide derived from human USP28 (Phospho-Ser67)
- Specificity:
- This antibody detects endogenous levels of USP28 (Phospho-Ser67) at Human, Mouse,Rat
- Formulation:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source:
- Polyclonal, Rabbit,IgG
- Dilution:
- WB 1:500-2000
- Purification:
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration:
- 1 mg/ml
- Storage Stability:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- Other Name:
- Ubiquitin carboxyl-terminal hydrolase 28 (EC 3.4.19.12) (Deubiquitinating enzyme 28) (Ubiquitin thioesterase 28) (Ubiquitin-specific-processing protease 28)
- Molecular Weight(Da):
- 118kD
- Background:
- The protein encoded by this gene is a deubiquitinase involved in the DNA damage pathway and DNA damage-induced apoptosis. Overexpression of this gene is seen in several cancers. [provided by RefSeq, Oct 2016],
- Function:
- catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UIM (ubiquitin-interacting motif) repeat.,
- Subcellular Location:
- Nucleus, nucleoplasm .
- Expression:
- Brain,Eye,
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- Antibody-FAQs
- Products Images
- Immunofluorescence analysis of MCF7 cell. 1,primary Antibody was diluted at 1:100(4°C overnight). 2, Goat Anti Rabbit IgG (H&L) - AFluor 594 Secondary antibody(catalog No: RS3611) was diluted at 1:500(room temperature, 50min).
- Western Blot analysis of various,using primary antibody at 1:1000 dilution. Secondary antibody(catalog#:RS23920) was diluted at 1:10000