• Target：
• SATB1

• Gene Name：
• SATB1

• Protein Name：
• SATB1 (Ser47)

• Human Gene Id：
• 6304

• Human Swiss Prot No：
• Q01826

• Mouse Gene Id：
• 20230

• Mouse Swiss Prot No：
• Q60611

• Immunogen：
• Synthesized phosho peptide around human SATB1 (Ser47)

• Specificity：
• This antibody detects endogenous levels of Human Mouse Rat SATB1 (phospho-Ser47)

• Formulation：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Source：
• Polyclonal, Rabbit,IgG

• Dilution：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• Purification：
• The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

• Concentration：
• 1 mg/ml

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• DNA-binding protein SATB1 (Special AT-rich sequence-binding protein 1)

• Observed Band(KD)：
• 85kD

• Background：
• This gene encodes a matrix protein which binds nuclear matrix and scaffold-associating DNAs through a unique nuclear architecture. The protein recruits chromatin-remodeling factors in order to regulate chromatin structure and gene expression. [provided by RefSeq, Apr 2016],

• Function：
• function:Binds to DNA at special AT-rich sequences at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA.,PTM:Sumoylated.,similarity:Belongs to the CUT homeobox family.,similarity:Contains 1 homeobox DNA-binding domain.,similarity:Contains 2 CUT DNA-binding domains.,tissue specificity:Expressed predominantly in thymus.,

• Subcellular Location：
• Nucleus matrix . Nucleus, PML body . Organized into a cage-like network anchoring loops of heterochromatin and tethering specialized DNA sequences (PubMed:12692553). When sumoylated, localized in promyelocytic leukemia nuclear bodies (PML NBs) (PubMed:18408014). .

• Expression：
• Expressed predominantly in thymus.

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