• Target：
• Aurora A

• Fields：
• >>Oocyte meiosis;>>Progesterone-mediated oocyte maturation

• Gene Name：
• AURKA AIK AIRK1 ARK1 AURA AYK1 BTAK IAK1 STK15 STK6

• Protein Name：
• Aurora A

• Human Gene Id：
• 6790

• Human Swiss Prot No：
• O14965

• Mouse Gene Id：
• 20878

• Mouse Swiss Prot No：
• P97477

• Rat Swiss Prot No：
• P59241

• Specificity：
• endogenous

• Formulation：
• PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

• Source：
• Monoclonal, rabbit, IgG, Kappa

• Dilution：
• IHC 1:200-1000,WB 1:1000-5000,IF 1:200-1000,ELISA 1:5000-20000,IP 1:50-200

• Purification：
• Protein A

• Storage Stability：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• Other Name：
• Aurora kinase A (EC 2.7.11.1) (Aurora 2) (Aurora/IPL1-related kinase 1) (ARK-1) (Aurora-related kinase 1) (hARK1) (Breast tumor-amplified kinase) (Serine/threonine-protein kinase 15) (Serine/threonine-protein kinase 6) (Serine/threonine-protein kinase aurora-A)

• Molecular Weight(Da)：
• 45kD

• Observed Band(KD)：
• 45kD

• Background：
• Aurora A(AURKA) Homo sapiens The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene.

• Subcellular Location：
• Membranous

• Expression：
• Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines.

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