β-actin Monoclonal Antibody(5B7), AbFluor™ 555 Conjugated

  • Catalog No.：YM2188
  • Applications：IF/ICC,WB,IHC-p
  • Reactivity：Human,Rat,Mouse,Mk,Dg,Ch,Hamster,Rb,Insect
    • Gene Name：
    • ACTB
    • Protein Name：
    • Actin cytoplasmic 1
    • Human Gene Id：
    • 60
    • Human Swiss Prot No：
    • P60709
    • Specificity：
    • β-actin Monoclonal Antibody(5B7) AbFluor™ 555 Conjugated specially designed for your Immunofluorescence analysis.
    • Formulation：
    • Liquid in PBS, pH 7.4, containing 0.02% sodium azide as preservative and 50% Glycerol.
    • Source：
    • Mouse IgG1
    • Dilution：
    • Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC: 1:200, IF 1:200.
    • Purification：
    • The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
    • Concentration：
    • 1mg/ml
    • Storage Stability：
    • Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and th
    • Other Name：
    • ACTB
    • Background：
    • actin beta(ACTB) Homo sapiens This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, and integrity. This actin is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins. [provided by RefSeq, Jul 2008],
    • Function：
    • disease:Defects in ACTB are a cause of dystonia juvenile-onset (DYTJ) [MIM:607371]. DYTJ is a form of dystonia with juvenile onset. Dystonia is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. DYTJ patients manifest progressive, generalized, dopa-unresponsive dystonia, developmental malformations and sensory hearing loss.,function:Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.,miscellaneous:In vertebrates 3 main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins coexist in most cell types as components of the cytoskeleton and as mediators of internal cell motility.,similarity:Belongs to the
    • Subcellular Location：
    • nuclear chromatin,extracellular space,nucleoplasm,cytoplasm,cytosol,cytoskeleton,plasma membrane,focal adhesion,membrane,intracellular ribonucleoprotein complex,cortical cytoskeleton,NuA4 histone acetyltransferase complex,cyt
    • Expression：
    • B-cell lymphoma,Brain,Cajal-Retzius cell,Eye,Fetal brain cortex,Foreskin,Hepatocellular car

    Attributes

    • Code：
    • YM2188
    • Size
    • 100ul
    • Price$：
    • 340
    • Delivery：
    • 2021-11-04
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