Recombinant Human CD117 protein ,C- His Tag
- Catalog No.:YD2221
- Reactivity:Human
- Purity:
- >90% as determined by SDS-PAGE
- In Vivo:
- < 1.0 EU per μg of the protein as determined by the LAL method.
- Sequence:
- A DNA sequence encoding the human KIT(Met1-IIe516) was fused with the C-terminal His Tag
- Human Swiss Prot No:
- P10721
- Formulation:
- Supplied as solution form in PBS pH 7.5./ Lyophilized from PBS pH 7.5.
- Source:
- Mammalian cells
- Dilution:
- Reconstitute in sterile water for a stock solution
- Concentration:
- >90% as determined by SDS-PAGE
- Storage Stability:
- Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week . Store at -20 to -80 °C for twelve months from the date of receipt.
- Other Name:
- KIT
- Subcellular Location:
- [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cytoplasm . Detected in the cytoplasm of spermatozoa, especially in the equatorial and subacrosomal region of the sperm head. .
- Expression:
- [Isoform 3]: In testis, detected in spermatogonia in the basal layer and in interstitial Leydig cells but not in Sertoli cells or spermatocytes inside the seminiferous tubules (at protein level) (PubMed:20601678). Expression is maintained in ejaculated spermatozoa (at protein level) (PubMed:20601678).
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