Recombinant Human IL1B protein ,C- His Tag

  • Catalog No.：YD2203
  • Reactivity：Human
    • Purity：
    • >90% as determined by SDS-PAGE
    • In Vivo：
    • Please contact with the lab for this information.
    • Sequence：
    • A DNA sequence encoding the human IL1B(Ala117~Ser269) was fused with the C-terminal His Tag
    • Human Swiss Prot No：
    • P01584
    • Formulation：
    • Supplied as solution form in PBS pH7.5./ Lyophilized from PBS pH7.5.
    • Source：
    • E.coli
    • Dilution：
    • Reconstitute in sterile water for a stock solution
    • Concentration：
    • >90% as determined by SDS-PAGE
    • Storage Stability：
    • Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week . Store at -20 to -80 °C for twelve months from the date of receipt.
    • Other Name：
    • IL1F2
    • Subcellular Location：
    • Cytoplasm, cytosol . Secreted . Lysosome . Secreted, extracellular exosome . The precursor is cytosolic (PubMed:15192144). In response to inflammasome-activating signals, such as ATP for NLRP3 inflammasome or bacterial flagellin for NLRC4 inflammasome, cleaved and secreted (PubMed:24201029, PubMed:33377178, PubMed:33883744). Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore (PubMed:33883744). In contrast, the precursor form is not released, due to the presence of an acidic region that is proteolytically removed by CASP1 during maturation (PubMed:33883744). The secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10 (PubMed:32272059). .
    • Expression：
    • Expressed in activated monocytes/macrophages (at protein level).

    Attributes

    • Code：
    • YD2203
    • Size
    • 100μg / 1mg
    • Price$：
    • 720 / 4320
    • Delivery：
    • 2024-12-08
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