Recombinant SARS-CoV-2(Covid-19) NSP10

  • Catalog No.:YD2188
  • Applications:ELISA ECL Immunogold
  • Reactivity:Human virus
    • Purity:
    • >90% as determined by SDS-PAGE
    • Fields:
    • For research use only .Not for use in clinical diagnostic procedures.
    • Gene Name:
    • ORF1ab
    • Protein Name:
    • nsp10,GFL
    • Source:
    • E.coli
    • Dilution:
    • Testing in progress
    • Concentration:
    • >90% as determined by SDS-PAGE
    • Storage Stability:
    • Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week . Store at -20 to -80 °C for twelve months from the date of receipt.
    • Molecular Weight(Da):
    • 17.99kDa
    • Observed Band(KD):
    • 18kDa
    • Background:
    • Recombinant SARS-CoV-2 NSP10 is produced by E.coli expression system and the target gene encoding Ala1-Gln139 is expressed with N-His Tag
    • Function:
    • Nsp10 have shown that it is a 15-kDa protein of unknown function that has been shown to interact with itself, nsp1, and nsp7. It colocalizes with N to sites of viral replication and is essential for replication. It plays a pivotal role in viral transcription by stimulating both nsp14 3'-5' exoribonuclease and nsp16 2'-O-methyltransferase activities. Therefore plays an essential role in viral mRNAs cap methylation. Nsp10 is a critical regulator of coronavirus RNA synthesis and may play an important role in polyprotein processing.