AMG337

    • Catalog No.:MC1058
      • CasNo:
      • 1173699-31-4
      • MolecularFormula:
      • C23H22FN7O3
      • Purity:
      • >98%
      • Target:
      • c-Met/HGFR
      • IC50:
      • No data
      • In Vitro:
      • In Vivo:
      • Fields:
      • AMG-337 is a potent and highly selective small molecule ATP-competitive MET kinase inhibitor. AMG 337 inhibits MET kinase activity with an IC50 of < 5nM in enzymatic assays.
      • Specificity:
      • Target: c-Met/HGFR. Fields: AMG-337 is a potent and highly selective small molecule ATP-competitive MET kinase inhibitor. AMG 337 inhibits MET kinase activity with an IC50 of < 5nM in enzymatic assay
      • Source:
      • Rabbit
      • Dilution:
      • WB 1:500-2000
      • Concentration:
      • >98%
      • Storage Stability:
      • 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
      • Other Name:
      • AMG 337,AMG-337
      • MolecularWeight(Da):
      • 463.46
      • References:
      • [1]. Paul E. Hughes, et al. AMG 337, a novel, potent and selective MET kinase inhibitor, has robust growth inhibitory activity in MET-dependent cancer models. Cancer Res October 1, 2014 74; 728[2]. C
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