Total MNK1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA4184C
  • Applications：ELISA
  • Reactivity：Human;Mouse
    • Gene Name：
    • MKNK1
    • Human Gene Id：
    • 8569
    • Human Swiss Prot No：
    • Q9BUB5
    • Mouse Swiss Prot No：
    • O08605
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • MAP kinase-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (MAP kinase signal-integrating kinase 1) (MAPK signal-integrating kinase 1) (Mnk1)
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Phosphorylated and activated by the p38 kinases and kinases in the Erk pathway.,function:May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.,PTM:Dual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with the C-terminal regions of EIF4G1 and EIF4G2. Also binds to dephosphorylated ERK1 and ERK2, and to the p38 kinases.,tissue specificity:Ubiquitous.,
    • Function：
    • regulation of translation, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, intracellular signaling cascade, protein kinase cascade, posttranscriptional regulation of gene expression,phosphorylation, regulation of cellular protein metabolic process,
    • Subcellular Location：
    • [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm. Nucleus.
    • Expression：
    • Ubiquitous.

    Attributes

    • Code：
    • KA4184C
    • Size
    • 96 / well
    • Price$：
    • 330
    • Delivery：
    • 2024-12-08
    Order

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