Total MEK1 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA4174C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • MAP2K1
    • Human Gene Id:
    • 5604
    • Human Swiss Prot No:
    • Q02750
    • Mouse Swiss Prot No:
    • P31938
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Dual specificity mitogen-activated protein kinase kinase 1 (MAP kinase kinase 1) (MAPKK 1) (MKK1) (EC 2.7.12.2) (ERK activator kinase 1) (MAPK/ERK kinase 1) (MEK 1)
    • Detection Method:
    • Colorimetric
    • Function:
    • M phase of mitotic cell cycle, MAPKKK cascade, activation of MAPK activity, mitotic cell cycle, M phase, nuclear division,cell morphogenesis, regulation of vascular smooth muscle contraction, regulation of transcription, DNA-dependent,regulation of transcription from RNA polymerase II promoter, protein complex assembly, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell motion, chemotaxis, regulation of muscle contraction, regulation of smooth muscle contraction, response to oxidative stress, microtubule-based process,microtubule-based movement, Golgi organization, cell cycle, mitosis, negative regulation of cell adhesion, intracellular signaling cascade, protein kinase cascade, small GTPase mediated signal transduction, Ras protein signal transduction, ectoderm development, behavior, locomotory behavior, cell proliferation, epidermis deve
    • Subcellular Location:
    • Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body . Cytoplasm . Nucleus . Membrane ; Peripheral membrane protein . Localizes at centrosomes during prometaphase, midzone during anaphase and midbody during telophase/cytokinesis (PubMed:14737111). Membrane localization is probably regulated by its interaction with KSR1 (PubMed:10409742). .
    • Expression:
    • Widely expressed, with extremely low levels in brain.