Total MMP-7 Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA3333C
  • Applications:ELISA
  • Reactivity:Human;Mouse;Rat
    • Gene Name:
    • MMP7
    • Human Gene Id:
    • 4316
    • Human Swiss Prot No:
    • P09237
    • Mouse Swiss Prot No:
    • Q10738
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase)
    • Detection Method:
    • Colorimetric
    • Background:
    • catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,
    • Function:
    • proteolysis, collagen catabolic process, collagen metabolic process, regulation of cell proliferation, multicellular organismal metabolic process, multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
    • Subcellular Location:
    • Secreted, extracellular space, extracellular matrix .