Total MMP-7 Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA3333C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- MMP7
- Human Gene Id:
- 4316
- Human Swiss Prot No:
- P09237
- Mouse Swiss Prot No:
- Q10738
- Rat Swiss Prot No:
- P50280
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Matrilysin (EC 3.4.24.23) (Matrin) (Matrix metalloproteinase-7) (MMP-7) (Pump-1 protease) (Uterine metalloproteinase)
- Detection Method:
- Colorimetric
- Background:
- catalytic activity:Cleavage of 14-Ala-|-Leu-15 and 16-Tyr-|-Leu-17 in B chain of insulin. No action on collagen types I, II, IV, V. Cleaves gelatin chain alpha-2(I) > alpha-1(I).,cofactor:Binds 2 calcium ions per subunit.,cofactor:Binds 2 zinc ions per subunit.,domain:The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.,function:Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.,similarity:Belongs to the peptidase M10A family.,
- Function:
- proteolysis, collagen catabolic process, collagen metabolic process, regulation of cell proliferation, multicellular organismal metabolic process, multicellular organismal catabolic process, multicellular organismal macromolecule metabolic process,
- Subcellular Location:
- Secreted, extracellular space, extracellular matrix .
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