Phospho IGF1R (Y1346) Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA1788C
- Applications:ELISA
- Reactivity:Human;Mouse;Rat
- Gene Name:
- IGF1R
- Human Gene Id:
- 3480
- Human Swiss Prot No:
- P08069
- Mouse Swiss Prot No:
- Q60751
- Rat Swiss Prot No:
- P24062
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain;Insulin-like growth factor 1 receptor beta chain]
- Detection Method:
- Colorimetric
- Function:
- cell morphogenesis, cell morphogenesis involved in differentiation, reproductive developmental process, regulation of DNA replication, protein complex assembly, protein amino acid phosphorylation, phosphorus metabolic process,phosphate metabolic process, anti-apoptosis, immune response, establishment or maintenance of cell polarity, cell surface receptor linked signal transduction, enzyme linked receptor protein signaling pathway, transmembrane receptor protein tyrosine kinase signaling pathway, intracellular signaling cascade, protein kinase cascade,axonogenesis, sex determination, positive regulation of cell proliferation, insulin receptor signaling pathway, response to endogenous stimulus, response to hormone stimulus, positive regulation of biosynthetic process, response to organic substance, positive regulation of macromolecule biosynthetic process, positive regulation of macromolec
- Subcellular Location:
- Cell membrane ; Single-pass type I membrane protein .
- Expression:
- Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney.
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