Phospho CD88/C5aR (S338) Cell-Based Colorimetric ELISA Kit

  • Catalog No.:KA1781C
  • Applications:ELISA
  • Reactivity:Human
    • Gene Name:
    • C5AR1
    • Human Gene Id:
    • 728
    • Human Swiss Prot No:
    • P21730
    • Mouse Swiss Prot No:
    • P30993
    • Storage Stability:
    • 2-8°C/6 months
    • Other Name:
    • C5a anaphylatoxin chemotactic receptor (C5a-R) (C5aR) (CD antigen CD88)
    • Detection Method:
    • Colorimetric
    • Background:
    • function:Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.,PTM:Sulfation plays a critical role in the association of the receptor with C5a, but no significant role in the ability of the receptor to transduce a signal and mobilize calcium in response to a small peptide agonist.,similarity:Belongs to the G-protein coupled receptor 1 family.,
    • Function:
    • MAPKKK cascade, activation of MAPK activity, protein amino acid phosphorylation, phosphorus metabolic process,phosphate metabolic process, cellular ion homeostasis, cellular calcium ion homeostasis, cellular metal ion homeostasis, chemotaxis, defense response, immune response, cellular defense response, cell surface receptor linked signal transduction, G-protein coupled receptor protein signaling pathway, activation of phospholipase C activity,elevation of cytosolic calcium ion concentration, intracellular signaling cascade, protein kinase cascade, sensory perception, sensory perception of chemical stimulus, behavior, locomotory behavior, regulation of phospholipase activity, positive regulation of phospholipase activity, positive regulation of phospholipase C activity, phosphorylation,regulation of phosphate metabolic process, cellular homeostasis, cellular cation homeostasis, cellular
    • Subcellular Location:
    • Cell membrane ; Multi-pass membrane protein . Cytoplasmic vesicle . Phosphorylated C5aR colocalizes with ARRB1 and ARRB2 in cytoplasmic vesicles. .