Phospho p70 S6 Kinase (S424) Cell-Based Colorimetric ELISA Kit

  • Catalog No.：KA1634C
  • Applications：ELISA
  • Reactivity：Human;Mouse;Rat
    • Gene Name：
    • RPS6KB1 STK14A P70S6K
    • Protein Name：
    • Ribosomal protein S6 kinase beta-1
    • Human Gene Id：
    • 6198
    • Human Swiss Prot No：
    • P23443
    • Mouse Swiss Prot No：
    • Q8BSK8
    • Storage Stability：
    • 2-8°C/6 months
    • Other Name：
    • Ribosomal protein S6 kinase beta-1 (S6K-beta-1) (S6K1) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 1) (P70S6K1) (p70-S6K 1) (Ribosomal protein S6 kinase I) (Serine/threonine-protein kinase 14A) (p70 ribosomal S6 kinase alpha) (p70 S6 kinase alpha) (p70 S6K-alpha) (p70 S6KA)
    • Detection Method：
    • Colorimetric
    • Background：
    • catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Activation by serine/threonine phosphorylation and protein kinase C, inactivated by type 2A phosphatase.,function:Phosphorylates specifically ribosomal protein S6 in response to insulin or several classes of mitogens.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with PPP1R9A/neurabin-1.,tissue specificity:Widely expressed.,
    • Function：
    • response to acid, response to molecule of bacterial origin, reproductive developmental process, skeletal muscle contraction, muscle system process, protein amino acid phosphorylation, phosphorus metabolic process, phosphate metabolic process, cell motion, muscle contraction, striated muscle contraction, intracellular signaling cascade, protein kinase cascade, gamete generation, germ cell development, aging, response to nutrient, behavior, learning or memory, memory, long-term memory, positive regulation of cell proliferation, response to temperature stimulus,response to heat, response to wounding, response to mechanical stimulus, response to bacterium, response to abiotic stimulus, response to toxin, response to endogenous stimulus, response to hormone stimulus, response to carbohydrate stimulus, response to hexose stimulus, response to glucose stimulus, response to extracellular stimulu
    • Subcellular Location：
    • Cell junction, synapse, synaptosome . Mitochondrion outer membrane. Mitochondrion. Colocalizes with URI1 at mitochondrion.; [Isoform Alpha I]: Nucleus. Cytoplasm.; [Isoform Alpha II]: Cytoplasm.
    • Expression：
    • Widely expressed.

    Attributes

    • Code：
    • KA1634C
    • Size
    • 96 / well
    • Price$：
    • 470
    • Delivery：
    • 2024-12-08
    Order

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