• Gene Name：
• SRF

• Human Gene Id：
• 6722

• Human Swiss Prot No：
• P11831

• Mouse Swiss Prot No：
• Q9JM73

• Storage Stability：
• 2-8°C/6 months

• Other Name：
• Serum response factor (SRF)

• Detection Method：
• Colorimetric

• Background：
• function:SRF is a transcription factor that binds to the serum response element (SRE), a short sequence of dyad symmetry located 300 bp to the 5' of the site of transcription initiation of some genes (such as FOS). Required for cardiac differentation and maturation.,PTM:Phosphorylated by PRKDC.,similarity:Contains 1 MADS-box domain.,subunit:Binds DNA as a multimer, probably a dimer. Interacts with MLLT7/FOXO4, NKX3A and SSRP1. Interacts with ARID2 and SRFBP1 (By similarity). Forms complexes with ARID2, MYOCD, NKX2-5 and SRFBP1.,

• Function：
• angiogenesis, blood vessel development, in utero embryonic development, blastocyst development, blastocyst formation, trophectodermal cell differentiation, vasculature development, heart looping, sprouting angiogenesis, cell migration during sprouting angiogenesis, heart morphogenesis, transcription, regulation of transcription, DNA-dependent, regulation of transcription from RNA polymerase II promoter, cell motion, regulation of muscle contraction,regulation of smooth muscle contraction, heart development, aging, response to wounding, response to toxin,response to endogenous stimulus, response to hormone stimulus, embryonic development ending in birth or egg hatching, positive regulation of biosynthetic process, response to organic substance, senescence, regulation of specific transcription from RNA polymerase II promoter, positive regulation of specific transcription from RNA polymeras

• Subcellular Location：
• Nucleus .

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