Phospho BIK (T33) Cell-Based Colorimetric ELISA Kit
- Catalog No.:KA1197C
- Applications:ELISA
- Reactivity:Human
- Gene Name:
- BIK
- Human Gene Id:
- 638
- Human Swiss Prot No:
- Q13323
- Mouse Swiss Prot No:
- O70337
- Storage Stability:
- 2-8°C/6 months
- Other Name:
- Bcl-2-interacting killer (Apoptosis inducer NBK) (BIP1) (BP4)
- Detection Method:
- Colorimetric
- Background:
- domain:Intact BH3 motif is required by BIK, BID, BAK, BAD and BAX for their pro-apoptotic activity and for their interaction with anti-apoptotic members of the Bcl-2 family.,function:Accelerates programmed cell death. Binding to the apoptosis repressors Bcl-X(L), BHRF1, Bcl-2 or its adenovirus homolog E1B 19k protein suppresses this death-promoting activity. Does not interact with BAX.,subcellular location:Around the nuclear envelope, and in cytoplasmic membranes.,
- Function:
- reproductive developmental process, apoptosis, induction of apoptosis, gamete generation, spermatogenesis, sex differentiation, cell death, gonad development, male gonad development, regulation of cell death, positive regulation of cell death, programmed cell death, induction of programmed cell death, death, sexual reproduction, multicellular organism reproduction, regulation of apoptosis, positive regulation of apoptosis, regulation of programmed cell death,positive regulation of programmed cell death, development of primary sexual characteristics, development of primary male sexual characteristics, male sex differentiation, male gamete generation, reproductive structure development,reproductive process in a multicellular organism,
- Subcellular Location:
- Endomembrane system; Single-pass membrane protein. Mitochondrion membrane ; Single-pass membrane protein . Around the nuclear envelope, and in cytoplasmic membranes.
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