• Target：
• Synaptophysin

• Gene Name：
• SYP

• Protein Name：
• Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI

• Human Swiss Prot No：
• P08247

• Mouse Swiss Prot No：
• Q62277

• Rat Swiss Prot No：
• P07825

• Immunogen：
• Synthesized peptide derived from human Synaptophysin AA range: 200-313

• Specificity：
• The antibody can specifically recognize human Synaptophysin protein.

• Source：
• Mouse, Monoclonal/IgG1, kappa

• Purification：
• The antibody was affinity-purified from ascites by affinity-chromatography using specific immunogen.

• Storage Stability：
• 2°C to 8°C/1 year

• Other Name：
• Major synaptic vesicle protein p38;MRX96;MRXSYP;Syn p38;Synaptophysin;Syp;SYPH;SYPH_HUMAN;SypI

• Background：
• This gene encodes an integral membrane protein of small synaptic vesicles in brain and endocrine cells. The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments. Mutations in this gene are associated with X-linked mental retardation (XLMR). [provided by RefSeq, Aug 2011],

• Function：
• domain:The calcium-binding activity is thought to be localized in the cytoplasmic tail of the protein.,function:Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane.,online information:Synaptophysin entry,PTM:Ubiquitinated; mediated by SIAH1 or SIAH2 and leading to its subsequent proteasomal degradation.,similarity:Belongs to the synaptophysin/synaptobrevin family.,similarity:Contains 1 MARVEL domain.,subunit:Homohexamer or homotetramer.,tissue specificity:Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.,

• Subcellular Location：
• Cytoplasmic

• Expression：
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