- 靶点:
- FDX1
- 基因名称:
- FDX1 ADX
- 蛋白名称:
- Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin)
- Human Gene Id:
- 2230
- Human Swiss Prot No:
- P10109
- Mouse Gene Id:
- 14148
- Mouse Swiss Prot No:
- P46656
- Rat Gene Id:
- 29189
- Rat Swiss Prot No:
- P24483
- 免疫原:
- Synthesized peptide derived from human N-ternal ADX
- 特异性:
- This antibody detects endogenous levels of ADX at Human, Mouse,Rat
- 组成:
- Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000 IHC 1:50-200
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 其他名称:
- Adrenodoxin, mitochondrial (Adrenal ferredoxin) (Ferredoxin-1) (Hepatoredoxin)
- 分子量:
- 20kD
- 功能:
- Essential for the synthesis of various steroid hormones . Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis . Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage . Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons (By similarity).
- 细胞定位:
- Mitochondrion matrix .
- 组织表达:
- Highest levels in the adrenal gland (at protein level). Also detected in kidney and testis (at protein level).
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