• 靶点：
• STXB2

• 基因名称：
• STXBP2 UNC18B

• 蛋白名称：
• STXB2

• Human Gene Id：
• 6813

• Human Swiss Prot No：
• Q15833

• Mouse Gene Id：
• 20911

• Mouse Swiss Prot No：
• Q64324

• Rat Gene Id：
• 81804

• Rat Swiss Prot No：
• Q62753

• 免疫原：
• Synthesized peptide derived from human STXB2 AA range: 392-442

• 特异性：
• This antibody detects endogenous levels of STXB2 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 65kD

• 背景：
• This gene encodes a member of the STXBP/unc-18/SEC1 family. The encoded protein is involved in intracellular trafficking, control of SNARE (soluble NSF attachment protein receptor) complex assembly, and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2013],

• 功能：
• function:Involved in the protein trafficking from the Golgi apparatus to the plasma membrane.,similarity:Belongs to the STXBP/unc-18/SEC1 family.,subunit:Binds syntaxins 1A, 2, 3 but not 4.,tissue specificity:Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.,

• 细胞定位：
• cytosol,plasma membrane,integral component of membrane,apical plasma membrane,SNARE complex,specific granule,azurophil granule,zymogen granule membrane,cytolytic granule,extracellular exosome,tertiary granule,

• 组织表达：
• Placenta, lung, liver, kidney and pancreas, as well as in peripheral blood lymphocytes.

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