• 靶点：
• JADE3

• 基因名称：
• PHF16 JADE3 KIAA0215

• 蛋白名称：
• JADE3

• Human Gene Id：
• 9767

• Human Swiss Prot No：
• Q92613

• Mouse Gene Id：
• 382207

• Mouse Swiss Prot No：
• Q6IE82

• 免疫原：
• Synthesized peptide derived from human JADE3 AA range: 484-534

• 特异性：
• This antibody detects endogenous levels of JADE3 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 91kD

• 背景：
• This gene encodes a member of a family of large proteins containing PHD (plant homeo domain)-type zinc fingers. The encoded protein may be associated in a nuclear complex that functions in histone H4 acetylation. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013],

• 功能：
• function:Component of the HBO1 complex which has a histone H4-specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.,induction:By estradiol in estrogen-responsive breast cancer cells.,similarity:Belongs to the JADE family.,similarity:Contains 1 PHD-type zinc finger.,subunit:Component of the HBO1 complex composed at least of ING4 or ING5, MYTS2/HBO1, EAF6, and one of PHF15, PHF16 and PHF17.,tissue specificity:Ubiquitously expressed, with highest levels in placenta and uterus.,

• 细胞定位：
• histone acetyltransferase complex,

• 组织表达：
• Ubiquitously expressed, with highest levels in placenta and uterus.

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