• 靶点：
• ROMO1

• 基因名称：
• ROMO1 C20orf52

• 蛋白名称：
• ROMO1

• Human Gene Id：
• 140823

• Human Swiss Prot No：
• P60602

• Mouse Gene Id：
• 67067

• Mouse Swiss Prot No：
• P60603

• 免疫原：
• Synthesized peptide derived from human ROMO1 AA range: 17-67

• 特异性：
• This antibody detects endogenous levels of ROMO1 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1：50-200. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 9kD

• 背景：
• The protein encoded by this gene is a mitochondrial membrane protein that is responsible for increasing the level of reactive oxygen species (ROS) in cells. The protein also has antimicrobial activity against a variety of bacteria by inducing bacterial membrane breakage. [provided by RefSeq, Nov 2014],

• 功能：
• developmental stage:Expression increases in senescent cells.,function:Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence.,induction:By the anticancer drug fluorouracil (5FU).,miscellaneous:Enforced expression in IMR-90 cells leads to increased levels of ROS and induces premature cell senescence and nuclear DNA damage.,similarity:Belongs to the MGR2 family.,tissue specificity:Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line.,

• 细胞定位：
• Mitochondrion inner membrane ; Single-pass membrane protein .

• 组织表达：
• Up-regulated in a number of cancer cell lines when compared to a normal lung fibroblast cell line. Highly expressed in brain tumors.

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