• 靶点：
• LRRN2

• 基因名称：
• LRRN2 GAC1 LRRN5 UNQ256/PRO293

• 蛋白名称：
• LRRN2

• Human Gene Id：
• 10446

• Human Swiss Prot No：
• O75325

• 免疫原：
• Synthesized peptide derived from human LRRN2 AA range: 296-346

• 特异性：
• This antibody detects endogenous levels of LRRN2 at Human

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 78kD

• 背景：
• The protein encoded by this gene belongs to the leucine-rich repeat superfamily. This gene was found to be amplified and overexpressed in malignant gliomas. The encoded protein has homology with other proteins that function as cell-adhesion molecules or as signal transduction receptors and is a candidate for the target gene in the 1q32.1 amplicon in malignant gliomas. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2008],

• 功能：
• similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 11 LRR (leucine-rich) repeats.,tissue specificity:Overamplified in malignant gliomas.,

• 细胞定位：
• Membrane ; Single-pass type I membrane protein .

• 组织表达：
• Overamplified in malignant gliomas.

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