KLF3 rabbit pAb

    • 货号:YT7584
    • 应用:WB;ELISA;IHC
    • 种属:Human;Mouse
      • 靶点:
      • KLF3
      • 简介:
      • >>Transcriptional misregulation in cancer
      • 基因名称:
      • KLF3 BKLF
      • 蛋白名称:
      • KLF3
      • Human Swiss Prot No:
      • P57682
      • Mouse Swiss Prot No:
      • Q60980
      • 免疫原:
      • Synthesized peptide derived from human KLF3 AA range: 51-101
      • 特异性:
      • This antibody detects endogenous levels of KLF3 at Human/Mouse
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 38kD
      • 功能:
      • function:Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis.,PTM:Sumoylated by SUMO1. Sumoylation is enhanced by PIAS1, PIAS2alpha and PIAS2beta, and PIAS4, but not by Pc2. Enhances transcriptional repression, but has no effect on DNA binding. Sumoylation on Lys-198 is the major site.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Monomer.,
      • 细胞定位:
      • Nucleus .
      • 产品图片
      • Western blot analysis of lysates from A431 cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human Breast cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).