• 靶点：
• SLIB

• 简介：
• >>Neuroactive ligand-receptor interaction;>>Growth hormone synthesis, secretion and action

• 基因名称：
• GHRH GHRF

• 蛋白名称：
• SLIB

• Human Gene Id：
• 2691

• Human Swiss Prot No：
• P01286

• Mouse Gene Id：
• 14601

• Mouse Swiss Prot No：
• P16043

• Rat Gene Id：
• 29446

• Rat Swiss Prot No：
• P09916

• 免疫原：
• Synthesized peptide derived from human SLIB AA range: 43-93

• 特异性：
• This antibody detects endogenous levels of SLIB at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• IHC 1：50-200. IF 1:50-200

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 12kD

• 背景：
• This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016],

• 功能：
• function:GRF is released by the hypothalamus and acts on the adenohypophyse to stimulate the secretion of growth hormone.,online information:Growth hormone releasing hormone entry,pharmaceutical:Available under the names Groliberin (Pharmacia) or Somatrel (Ferring). Also available under the name Geref (Serono). Geref is a synthetic acetylated form of residues 1 to 29 of GHRH. Used for the treatment of growth hormone deficiency.,similarity:Belongs to the glucagon family.,

• 细胞定位：
• Secreted.

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