- 靶点：
- AAAT
- 简介：
- >>Protein digestion and absorption;>>Central carbon metabolism in cancer
- 基因名称：
- SLC1A5 ASCT2 M7V1 RDR RDRC
- 蛋白名称：
- AAAT
- Human Gene Id：
- 6510
- Human Swiss Prot No：
- Q15758
- Mouse Swiss Prot No：
- P51912
- 免疫原：
- Synthesized peptide derived from human AAAT AA range: 345-395
- 特异性：
- This antibody detects endogenous levels of AAAT at Human/Mouse
- 组成：
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源：
- Polyclonal, Rabbit,IgG
- 稀释：
- WB 1：500-2000
- 纯化工艺：
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度：
- 1 mg/ml
- 储存：
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 分子量：
- 60kD
- 背景：
- The SLC1A5 gene encodes a sodium-dependent neutral amino acid transporter that can act as a receptor for RD114/type D retrovirus (Larriba et al., 2001 [PubMed 11781704]).[supplied by OMIM, Jan 2011],
- 功能：
- alternative products:A number of isoforms are produced by alternative initiation. Isoforms start at multiple alternative CUG and GUG codons,function:Has a broad substrate specificity, a preference for zwitterionic amino acids, and a sodium-dependence. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated amino acids, anionic amino acids, and cationic amino acids. Act as a cell surface receptor for feline endogenous virus RD114, baboon M7 endogenous virus and type D simian retroviruses.,similarity:Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family.,subcellular location:Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,tissue specificity:Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.,
- 细胞定位：
- Cell membrane ; Multi-pass membrane protein . Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
- 组织表达：
- Placenta, lung, skeletal muscle, kidney, pancreas, and intestine.
A Preliminary Study on the Pathogenesis of Colorectal Cancer by Constructing a Hsa-circRNA-0067835-miRNA-mRNA Regulatory Network. OncoTargets and Therapy Oncotargets Ther. 2021; 14: 4645–4658 WB Human 1:1000 SW480 cell
货号：YT7482
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- Antibody-FAQs
- 产品图片
- Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
