• 靶点：
• IDI1

• 简介：
• >>Terpenoid backbone biosynthesis;>>Metabolic pathways

• 基因名称：
• IDI1

• 蛋白名称：
• IDI1

• Human Gene Id：
• 3422

• Human Swiss Prot No：
• Q13907

• Mouse Gene Id：
• 319554

• Mouse Swiss Prot No：
• P58044

• Rat Gene Id：
• 89784

• Rat Swiss Prot No：
• O35760

• 免疫原：
• Synthesized peptide derived from human IDI1 AA range: 103-153

• 特异性：
• This antibody detects endogenous levels of IDI1 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 25kD

• 背景：
• IDI1 encodes a peroxisomally-localized enzyme that catalyzes the interconversion of isopentenyl diphosphate (IPP) to its highly electrophilic isomer, dimethylallyl diphosphate (DMAPP), which are the substrates for the successive reaction that results in the synthesis of farnesyl diphosphate and, ultimately, cholesterol. It has been shown in peroxisomal deficiency diseases such as Zellweger syndrome and neonatal adrenoleukodystrophy that there is reduction in IPP isomerase activity. [provided by RefSeq, Jul 2008],

• 功能：
• catalytic activity:Isopentenyl diphosphate = dimethylallyl diphosphate.,cofactor:Binds 1 magnesium ion per subunit.,function:Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP).,pathway:Isoprenoid biosynthesis; dimethylallyl-PP biosynthesis; dimethylallyl-PP from isopentenyl-PP: step 1/1.,similarity:Belongs to the IPP isomerase type 1 family.,subunit:Monomer.,

• 细胞定位：
• Peroxisome .

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