AP4B1 rabbit pAb

    • 货号:YT7451
    • 应用:WB
    • 种属:Human;Mouse
      • 靶点:
      • AP4B1
      • 简介:
      • >>Lysosome
      • 基因名称:
      • AP4B1
      • 蛋白名称:
      • AP4B1
      • Human Swiss Prot No:
      • Q9Y6B7
      • Mouse Swiss Prot No:
      • Q9WV76
      • 免疫原:
      • Synthesized peptide derived from human AP4B1 AA range: 595-645
      • 特异性:
      • This antibody detects endogenous levels of AP4B1 at Human/Mouse
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 81kD
      • 背景:
      • This gene encodes a subunit of a heterotetrameric adapter-like complex 4 that is involved in targeting proteins from the trans-Golgi network to the endosomal-lysosomal system. Mutations in this gene are associated with cerebral palsy spastic quadriplegic type 5 (CPSQ5) disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011],
      • 功能:
      • function:Subunit of novel type of clathrin- or non-clathrin-associated protein coat involved in targeting proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system.,similarity:Belongs to the adaptor complexes large subunit family.,subcellular location:Associated with the trans-Golgi network. Found in soma and dendritic shafts of neuronal cells.,subunit:Adapter-like complex 4 (AP-4) is a heterotetramer composed of two large adaptins (epsilon-type subunit AP4E1 and beta-type subunit AP4B1), a medium adaptin (mu-type subunit AP4M1) and a small adaptin (sigma-type AP4S1).,tissue specificity:Widely expressed.,
      • 细胞定位:
      • Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein .
      • 组织表达:
      • Widely expressed.
      • 产品图片
      • Western blot analysis of lysates from HEK293 cells, primary antibody was diluted at 1:1000, 4°over night