- 靶点:
- MSMO1
- 简介:
- >>Steroid biosynthesis;>>Metabolic pathways
- 基因名称:
- MSMO1 DESP4 ERG25 SC4MOL
- 蛋白名称:
- MSMO1
- Human Gene Id:
- 6307
- Human Swiss Prot No:
- Q15800
- Mouse Gene Id:
- 66234
- Mouse Swiss Prot No:
- Q9CRA4
- Rat Gene Id:
- 140910
- Rat Swiss Prot No:
- O35532
- 免疫原:
- Synthesized peptide derived from human MSMO1 AA range: 212-262
- 特异性:
- This antibody detects endogenous levels of MSMO1 at Human/Mouse/Rat
- 组成:
- Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- 来源:
- Polyclonal, Rabbit,IgG
- 稀释:
- WB 1:500-2000;IHC 1:50-300
- 纯化工艺:
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- 浓度:
- 1 mg/ml
- 储存:
- -15°C to -25°C/1 year(Do not lower than -25°C)
- 分子量:
- 32kD
- 背景:
- Sterol-C4-mehtyl oxidase-like protein was isolated based on its similarity to the yeast ERG25 protein. It contains a set of putative metal binding motifs with similarity to that seen in a family of membrane desaturases-hydroxylases. The protein is localized to the endoplasmic reticulum membrane and is believed to function in cholesterol biosynthesis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
- 功能:
- catalytic activity:3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carbaldehyde + NAD(P)H + O(2) = 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carboxylate + NAD(P)(+) + H(2)O.,catalytic activity:4,4-dimethyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) = 4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)(+) + H(2)O.,catalytic activity:4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholest-7-en-3-beta-ol + NAD(P)H + O(2) = 3-beta-hydroxy-4-beta-methyl-5-alpha-cholest-7-ene-4-alpha-carbaldehyde + NAD(P)(+) + 2 H(2)O.,cofactor:Iron.,domain:The histidine box domains may contain the active site and/or be involved in metal ion binding.,pathway:Steroid biosynthesis; zymosterol biosynthesis; zymosterol from lanosterol: step 3/6.,similarity:Belongs to the sterol desaturase family.,
- 细胞定位:
- Endoplasmic reticulum membrane ; Multi-pass membrane protein .
CCR9 overexpression promotes T-ALL progression by enhancing cholesterol biosynthesis. Frontiers in Pharmacology Quiping Zhang WB Human 1:1000 JURKAT cell
货号:YT7443
miR-19b-3p Regulated by Estrogen Controls Lipid Synthesis Through Targeting MSMO1 and ELOVL5 in LMH Cells. POULTRY SCIENCE Hong Li WB Chicken LMH cell
货号:YT7443
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- Antibody-FAQs
- 产品图片
- Western blot analysis of lysates from KB cells, primary antibody was diluted at 1:1000, 4°over night
- Immunohistochemical analysis of paraffin-embedded human lung cancer. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).