• 靶点：
• CLCB

• 简介：
• >>Lysosome;>>Endocytosis;>>Synaptic vesicle cycle;>>Endocrine and other factor-regulated calcium reabsorption;>>Huntington disease;>>Bacterial invasion of epithelial cells

• 基因名称：
• CLTB

• 蛋白名称：
• CLCB

• Human Gene Id：
• 1212

• Human Swiss Prot No：
• P09497

• Mouse Gene Id：
• 74325

• Mouse Swiss Prot No：
• Q6IRU5

• Rat Gene Id：
• 116561

• Rat Swiss Prot No：
• P08082

• 免疫原：
• Synthesized peptide derived from human CLCB AA range: 168-218

• 特异性：
• This antibody detects endogenous levels of CLCB at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 25kD

• 背景：
• Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008],

• 功能：
• function:Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.,subcellular location:Cytoplasmic face of coated pits and vesicles.,subunit:Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R.,

• 细胞定位：
• Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic face of coated pits and vesicles.

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