• 靶点：
• RAB3A

• 简介：
• >>Synaptic vesicle cycle;>>Insulin secretion

• 基因名称：
• RAB3A

• 蛋白名称：
• RAB3A

• Human Gene Id：
• 5864

• Human Swiss Prot No：
• P20336

• Mouse Gene Id：
• 19339

• Mouse Swiss Prot No：
• P63011

• Rat Gene Id：
• 25531

• Rat Swiss Prot No：
• P63012

• 免疫原：
• Synthesized peptide derived from human RAB3A AA range: 27-77

• 特异性：
• This antibody detects endogenous levels of RAB3A at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 24kD

• 功能：
• function:Involved in exocytosis by regulating a late step in synaptic vesicle fusion. Could play a role in neurotransmitter release by regulating membrane flow in the nerve terminal.,similarity:Belongs to the small GTPase superfamily. Rab family.,subunit:Heterodimer with RIMS2. Part of a ternary complex involving PCLO and EPAC2. Interacts with RPH3A. Interacts with the exocyst complex through SEC15. Binds SYTL4, RIMS1 and RIMS2. Interacts with RAB3IP. Interacts with SGSM1 and SGSM3.,tissue specificity:Specifically expressed in brain.,

• 细胞定位：
• Cytoplasm, cytosol . Lysosome . Cytoplasmic vesicle, secretory vesicle . Cell projection, axon . Cell membrane ; Lipid-anchor ; Cytoplasmic side . Cell junction, synapse, presynapse . Cell junction, synapse, postsynapse . Cycles between a vesicle-associated GTP-bound form and a cytosolic GDP-bound form. .

• 组织表达：
• Specifically expressed in brain.

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