LCMT2 rabbit pAb

    • 货号:YT7278
    • 应用:WB;ELISA;IHC
    • 种属:Human;Mouse;Rat
      • 靶点:
      • LCMT2
      • 基因名称:
      • LCMT2 KIAA0547 TYW4
      • 蛋白名称:
      • LCMT2
      • Human Gene Id:
      • 9836
      • Human Swiss Prot No:
      • O60294
      • Mouse Swiss Prot No:
      • Q8BYR1
      • 免疫原:
      • Synthesized peptide derived from human LCMT2 AA range: 298-348
      • 特异性:
      • This antibody detects endogenous levels of LCMT2 at Human/Mouse/Rat
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 75kD
      • 背景:
      • The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq, Jul 2008],
      • 功能:
      • function:Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA (By similarity). May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues.,pathway:tRNA modification; wybutosine-tRNA(Phe) biosynthesis.,similarity:Belongs to the methyltransferase superfamily. LCMT family.,subunit:Interacts with RNF144B/IBRDC2.,
      • 细胞定位:
      • cytoplasm,cytosol,
      • 产品图片
      • Western blot analysis of lysates from PC-12 cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human Squamous cell carcinoma of lung. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).