• 靶点：
• AL1L2

• 简介：
• >>One carbon pool by folate;>>Metabolic pathways

• 基因名称：
• ALDH1L2

• 蛋白名称：
• AL1L2

• Human Gene Id：
• 160428

• Human Swiss Prot No：
• Q3SY69

• Mouse Gene Id：
• 216188

• Mouse Swiss Prot No：
• Q8K009

• 免疫原：
• Synthesized peptide derived from human AL1L2 AA range: 74-124

• 特异性：
• This antibody detects endogenous levels of AL1L2 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 102kD

• 背景：
• This gene encodes a member of both the aldehyde dehydrogenase superfamily and the formyl transferase superfamily. This member is the mitochondrial form of 10-formyltetrahydrofolate dehydrogenase (FDH), which converts 10-formyltetrahydrofolate to tetrahydrofolate and CO2 in an NADP(+)-dependent reaction, and plays an essential role in the distribution of one-carbon groups between the cytosolic and mitochondrial compartments of the cell. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010],

• 功能：
• catalytic activity:10-formyltetrahydrofolate + NADP(+) + H(2)O = tetrahydrofolate + CO(2) + NADPH.,sequence caution:Wrong choice of CDS.,similarity:Belongs to the aldehyde dehydrogenase family.,similarity:Contains 1 acyl carrier domain.,similarity:In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily.,similarity:In the N-terminal section; belongs to the GART family.,

• 细胞定位：
• Mitochondrion .

• 组织表达：
• Highly expressed in pancreas, heart, brain and skeletal muscle.

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