ROP1A rabbit pAb

    • 货号:YT7183
    • 应用:WB;IHC
    • 种属:Human;Rat;Mouse;
      • 靶点:
      • ROP1A
      • 基因名称:
      • ROPN1 ROPN1A
      • 蛋白名称:
      • ROP1A
      • Human Swiss Prot No:
      • Q9HAT0
      • 免疫原:
      • Synthesized peptide derived from human ROP1A AA range: 85-135
      • 特异性:
      • This antibody detects endogenous levels of ROP1A at Human
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000;IHC 1:50-300
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 23kD
      • 背景:
      • The protein encoded by this gene is found in the fibrous sheath of spermatazoa, where it interacts with rhophilin, a Rho GTPase binding protein. The encoded protein also can bind an A-kinase anchoring protein (AKAP110) and a calcium-binding tyrosine phosphorylation-regulated protein (CABYR). This protein may be involved in sperm motility and has been shown to be a cancer-testis antigen in hematologic malignancies. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015],
      • 功能:
      • developmental stage:Expressed in fetal liver.,domain:The RIIa domain mediates interaction with AKAP3.,miscellaneous:The name 'ropporin' comes from the Japanese word 'oppo' which means 'tail'.,similarity:Belongs to the ropporin family.,similarity:Contains 1 RIIa domain.,subcellular location:In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath.,subunit:Homodimer. Interacts with AKAP3 and RHPN1 (By similarity). May interact with SPA17.,tissue specificity:Testis specific in adult. Overexpressed in hematologic tumor cells.,
      • 细胞定位:
      • Cell projection, cilium, flagellum . In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath. .
      • 组织表达:
      • Testis specific in adult. Overexpressed in hematologic tumor cells.
      • 产品图片
      • Western blot analysis of lysates from Hela cells, primary antibody was diluted at 1:1000, 4°over night
      • Immunohistochemical analysis of paraffin-embedded human tonsil. 1, Antibody was diluted at 1:200(4° overnight). 2, Tris-EDTA,pH9.0 was used for antigen retrieval. 3,Secondary antibody was diluted at 1:200(room temperature, 45min).