• 靶点：
• ARL8B

• 简介：
• >>Salmonella infection

• 基因名称：
• ARL8B ARL10C GIE1

• 蛋白名称：
• ARL8B

• Human Gene Id：
• 55207

• Human Swiss Prot No：
• Q9NVJ2

• Mouse Gene Id：
• 67166

• Mouse Swiss Prot No：
• Q9CQW2

• Rat Gene Id：
• 500282

• Rat Swiss Prot No：
• Q66HA6

• 免疫原：
• Synthesized peptide derived from human ARL8B AA range: 9-59

• 特异性：
• This antibody detects endogenous levels of ARL8B at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 20kD

• 功能：
• function:May play a role in lysosomes motility (PubMed:16537643). May play a role in chromosomes segregation (PubMed:15331635).,similarity:Belongs to the small GTPase superfamily. Arf family.,subcellular location:According to PubMed:15331635 it localizes with microtubules at the spindle mid-zone during mitosis.,subunit:Interacts with tubulin.,tissue specificity:Ubiquitously expressed.,

• 细胞定位：
• Late endosome membrane . Lysosome membrane . Cytoplasm, cytoskeleton, spindle . Cell projection, axon . Cell junction, synapse . Cytolytic granule membrane . GTP-bound form resides on lysosomal membranes, whereas GDP-bound form is likely associated with microtubular structures (PubMed:16650381). Localizes with microtubules at the spindle mid-zone during mitosis. In dendritic cells, localizes to MHC II+ compartments (By similarity). .

• 组织表达：
• Ubiquitously expressed.

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