• 靶点：
• PSD10

• 基因名称：
• PSMD10

• 蛋白名称：
• PSD10

• Human Gene Id：
• 5716

• Human Swiss Prot No：
• O75832

• Mouse Swiss Prot No：
• Q9Z2X2

• Rat Gene Id：
• 116722

• Rat Swiss Prot No：
• Q9Z2X3

• 免疫原：
• Synthesized peptide derived from human PSD10 AA range: 86-136

• 特异性：
• This antibody detects endogenous levels of PSD10 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300; ELISA 2000-20000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 25kD

• 背景：
• This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.[provided by RefSeq, Mar 2011],

• 功能：
• function:Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins.,similarity:Contains 7 ANK repeats.,subunit:Component of the PA700 complex.,

• 细胞定位：
• Cytoplasm . Nucleus .

• 组织表达：
• Tends to be up-regulated in cancer cells with RAS mutations, including lung cancers and adenocarconimas (at protein level).

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