• 靶点：
• JAZF1

• 基因名称：
• JAZF1 TIP27 ZNF802

• 蛋白名称：
• JAZF1

• Human Gene Id：
• 221895

• Human Swiss Prot No：
• Q86VZ6

• Mouse Gene Id：
• 231986

• Mouse Swiss Prot No：
• Q80ZQ5

• 免疫原：
• Synthesized peptide derived from human JAZF1 AA range: 57-107

• 特异性：
• This antibody detects endogenous levels of JAZF1 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 27kD

• 背景：
• This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008],

• 功能：
• disease:A chromosomal aberration involving JAZF1 may be a cause of endometrial stromal tumors. Translocation t(7;17)(p15;q21) with SUZ12. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer.,function:Potential transcription factor.,similarity:Contains 3 C2H2-type zinc fingers.,subunit:Interacts with TAK1.,

• 细胞定位：
• Nucleus .

• 组织表达：
• Highest expression in testis with moderate levels in colon, placenta, prostate and ovary and low levels in brain, spleen, liver and small intestine.

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