CLLU1 rabbit pAb

    • 货号:YT6935
    • 应用:WB
    • 种属:Human
      • 靶点:
      • CLLU1
      • 基因名称:
      • CLLU1
      • 蛋白名称:
      • CLLU1
      • Human Swiss Prot No:
      • Q5K131
      • 免疫原:
      • Synthesized peptide derived from human CLLU1 AA range: 23-73
      • 特异性:
      • This antibody detects endogenous levels of CLLU1 at Human
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 13kD
      • 背景:
      • The protein encoded by this gene is overexpressed in chronic lymphocytic leukemia (CLL) and serves as a good prognostic marker for the disease. Methylation of certain genes, including this one, have been associated with CLL. This gene is protein-coding in humans and non-protein coding in other primates. Three transcript variants, one protein-coding and the other two non-protein coding, have been found for this gene. [provided by RefSeq, Nov 2015],
      • 功能:
      • disease:High CLLU1 expression in patients with CLL is associated with poor clinical outcome.,miscellaneous:Tridimensional modeling predicts that it may interact with the IL-4 receptor.,tissue specificity:Specifically expressed in chronic lymphocytic leukemia (CLL) cells from patients without immunoglobulin heavy-chain hypermutations.,
      • 细胞定位:
      • Cytoplasm . Detected in the cytoplasm of chronic lymphocytic leukemia (CLL) cells.
      • 组织表达:
      • Specifically expressed in chronic lymphocytic leukemia (CLL) cells from patients without immunoglobulin heavy-chain hypermutations. Expression is detected in all CLL cells and levels are similar in patients before and after treatment.
      • 产品图片
      • Western blot analysis of lysates from 3T3 cells, primary antibody was diluted at 1:1000, 4°over night