• 靶点：
• IMA8

• 简介：
• >>Nucleocytoplasmic transport;>>Influenza A;>>Chemical carcinogenesis - receptor activation

• 基因名称：
• KPNA7

• 蛋白名称：
• IMA8

• Human Gene Id：
• 402569

• Human Swiss Prot No：
• A9QM74

• Mouse Gene Id：
• 381686

• Mouse Swiss Prot No：
• C0LLJ0

• 免疫原：
• Synthesized peptide derived from human IMA8 AA range: 313-363

• 特异性：
• This antibody detects endogenous levels of IMA8 at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 57kD

• 背景：
• The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC), which consists of 60-100 proteins. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion while larger molecules are transported by an active process. The protein encoded by this gene belongs to the importin alpha family, and is involved in nuclear protein import, but exhibits different nuclear localization signal binding specificity compared to other members of the family. A pseudogene of this gene has been defined on chromosome 5. [provided by RefSeq, Jul 2016],

• 功能：
• function:Functions in nuclear protein import.,similarity:Belongs to the importin alpha family.,similarity:Contains 1 IBB domain.,similarity:Contains 8 ARM repeats.,

• 细胞定位：
• Nucleus .

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