• 靶点：
• PIGO

• 简介：
• >>Glycosylphosphatidylinositol (GPI)-anchor biosynthesis;>>Metabolic pathways

• 基因名称：
• PIGO UNQ632/PRO1249

• 蛋白名称：
• PIGO

• Human Gene Id：
• 84720

• Human Swiss Prot No：
• Q8TEQ8

• Mouse Swiss Prot No：
• Q9JJI6

• 免疫原：
• Synthesized peptide derived from human PIGO AA range: 950-1000

• 特异性：
• This antibody detects endogenous levels of PIGO at Human/Mouse

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1:500-2000;IHC 1:50-300

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 120kD

• 背景：
• This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011],

• 功能：
• alternative products:Additional isoforms seem to exist,function:Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI third mannose which links the GPI-anchor to the C-terminus of the proteins by an amide bond.,pathway:Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.,similarity:Belongs to the PIGG/PIGN/PIGO family. PIGO subfamily.,subunit:Forms a complex with PIGF. PIGF is required to stabilize PIGO.,

• 细胞定位：
• Endoplasmic reticulum membrane ; Multi-pass membrane protein .

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