• 靶点：
• EIF3I

• 基因名称：
• EIF3I EIF3S2 TRIP1

• 蛋白名称：
• EIF3I

• Human Gene Id：
• 8668

• Human Swiss Prot No：
• Q13347

• Mouse Gene Id：
• 54709

• Mouse Swiss Prot No：
• Q9QZD9

• Rat Gene Id：
• 682390

• Rat Swiss Prot No：
• B0BNA7

• 免疫原：
• Synthesized peptide derived from human EIF3I AA range: 100-150

• 特异性：
• This antibody detects endogenous levels of EIF3I at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 36kD

• 功能：
• function:Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.,mass spectrometry: PubMed:17322308,mass spectrometry: PubMed:18599441,PTM:Phosphorylated by TGF-beta type II receptor.,similarity:Belongs to the eIF-3 subunit I family.,similarity:Contains 5 WD repeats.,subunit:Component of the eukaryotic

• 细胞定位：
• Cytoplasm .

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