• 靶点：
• ADAMTSL4

• 基因名称：
• ADAMTSL4 TSRC1 PP1396 UNQ2803/PRO34012

• 蛋白名称：
• ADAMTSL4

• Human Gene Id：
• 54507

• Human Swiss Prot No：
• Q6UY14

• Mouse Gene Id：
• 229595

• Mouse Swiss Prot No：
• Q80T21

• Rat Gene Id：
• 310670

• Rat Swiss Prot No：
• Q4FZU4

• 免疫原：
• Synthesized peptide derived from human ATL4 AA range: 78-128

• 特异性：
• This antibody detects endogenous levels of ATL4 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 118kD

• 背景：
• This gene is a member of ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs)-like gene family and encodes a protein with seven thrombospondin type 1 repeats. The thrombospondin type 1 repeat domain is found in many proteins with diverse biological functions including cellular adhesion, angiogenesis, and patterning of the developing nervous system. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Sep 2014],

• 功能：
• caution:Although similar to members of the ADAMTS family, it lacks the metalloprotease and disintegrin-like domains which are typical of that family.,function:Positive regulation of apoptosis.,similarity:Contains 1 PLAC domain.,similarity:Contains 6 TSP type-1 domains.,subunit:Interacts with CTSB.,

• 细胞定位：
• Secreted, extracellular space, extracellular matrix . Colocalizes with FMN1 microfibrils in the eye ECM.

• 组织表达：
• Expressed in colon, heart, leukocyte, liver, lung, skeletal muscle, spleen, testis and placenta. Weaker expression in bone marrow, brain tissue, kidney and pancreas. Expression studies in fetal tissues reveal strong expression in heart, kidney, liver, lung and skeletal muscle, but weaker expression in fetal brain and skin.

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