• 靶点：
• FBX6

• 简介：
• >>Protein processing in endoplasmic reticulum

• 基因名称：
• FBXO6 FBG2 FBS2 FBX6

• 蛋白名称：
• FBX6

• Human Gene Id：
• 26270

• Human Swiss Prot No：
• Q9NRD1

• Mouse Gene Id：
• 50762

• Mouse Swiss Prot No：
• Q9QZN4

• Rat Gene Id：
• 192351

• Rat Swiss Prot No：
• Q923V4

• 免疫原：
• Synthesized peptide derived from human FBX6 AA range: 30-80

• 特异性：
• This antibody detects endogenous levels of FBX6 at Human/Mouse/Rat

• 组成：
• Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• 来源：
• Polyclonal, Rabbit,IgG

• 稀释：
• WB 1：500-2000

• 纯化工艺：
• The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• 浓度：
• 1 mg/ml

• 储存：
• -15°C to -25°C/1 year(Do not lower than -25°C)

• 分子量：
• 32kD

• 背景：
• This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq, Jul 2008],

• 功能：
• function:Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.,online information:hFBG2,similarity:Contains 1 F-box domain.,similarity:Contains 1 FBA (F-box associated) domain.,subunit:Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,

• 细胞定位：
• Cytoplasm .

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