NDK7 rabbit pAb

    • 货号:YT6676
    • 应用:WB
    • 种属:Human;Mouse;Rat
      • 靶点:
      • NDK7
      • 简介:
      • >>Purine metabolism;>>Pyrimidine metabolism;>>Drug metabolism - other enzymes;>>Metabolic pathways;>>Nucleotide metabolism;>>Biosynthesis of cofactors
      • 基因名称:
      • NME7
      • 蛋白名称:
      • NDK7
      • Human Swiss Prot No:
      • Q9Y5B8
      • Mouse Swiss Prot No:
      • Q9QXL8
      • 免疫原:
      • Synthesized peptide derived from human NDK7 AA range: 152-202
      • 特异性:
      • This antibody detects endogenous levels of NDK7 at Human/Mouse/Rat
      • 组成:
      • Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
      • 来源:
      • Polyclonal, Rabbit,IgG
      • 稀释:
      • WB 1:500-2000
      • 纯化工艺:
      • The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
      • 浓度:
      • 1 mg/ml
      • 储存:
      • -15°C to -25°C/1 year(Do not lower than -25°C)
      • 分子量:
      • 41kD
      • 背景:
      • This gene encodes a member of the non-metastatic expressed family of nucleoside diphosphate kinases. Members of this family are enzymes that catalyzes phosphate transfer from nucleoside triphosphates to nucleoside diphosphates. This protein contains two kinase domains, one of which is involved in autophosphorylation and the other may be inactive. This protein localizes to the centrosome and functions as a component of the gamma-tubulin ring complex which plays a role in microtubule organization. Mutations in this gene may be associated with venous thromboembolism. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016],
      • 功能:
      • catalytic activity:ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.,cofactor:Magnesium.,function:Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.,similarity:Belongs to the NDK family.,similarity:Contains 1 DM10 domain.,
      • 细胞定位:
      • centrosome,
      • 产品图片
      • Western blot analysis of lysates from HpeG2 cells, primary antibody was diluted at 1:1000, 4°over night